![]() The prior study examined data from the 12 flu seasons and identified an association between flu vaccination early in pregnancy and spontaneous abortion (miscarriage), particularly among people who had received flu vaccine during the previous flu season. This study was conducted as a follow-up to a previous smaller study. The study found no increased risk for miscarriage after flu vaccination during pregnancy. The study covered three flu seasons (2012-13, 2013-14, 2014-15) looking for any increased risk for miscarriage among pregnant people who had received a flu vaccine during their pregnancy. One of these studies was conducted using CDC’s Vaccine Safety Datalink (VSD). Multiple studies have shown that people who have received flu shots during pregnancy have not had a higher risk of spontaneous abortion (miscarriage). Can flu vaccination result in miscarriage? There is a large body of scientific studies that supports the safety of flu vaccine in pregnant people and their babies, and CDC continues to gather data on this topic. Flu shots have been given to millions of people over many years with an excellent safety record. Is it safe for pregnant people and their developing babies to get a flu shot? Earlier vaccination (e.g., in July or August) can be considered for people who are in the third trimester of pregnancy during those months. Influenza vaccine can be given during any trimester of pregnancy. September and October are generally good times to be vaccinated each year. ![]() A list of recent studies on the benefits of flu vaccination for pregnant people is available. Pregnant people who get a flu vaccine also are helping to protect their babies from flu illness and flu related hospitalizations for the first several months after their birth, when they are too young to get vaccinated. ![]() A 2018 study showed that getting a flu shot reduced a pregnant person’s risk of being hospitalized with flu by an average of 40%. These results are consistent with the general range of estimated flu vaccine effectiveness among adults 18-64 years. A 2013 study showed that during the 2010–20–2012 flu seasons vaccination reduced the risk of flu-associated acute respiratory infection in pregnant people by up to one-half. Flu shots given during pregnancy help protect both the pregnant parent and the baby from flu. Pregnant people should get a flu shot and not the nasal spray flu vaccine. Getting an influenza (flu) vaccine is the first and most important step to protect against flu. A Flu Vaccine is the Best Protection Against Flu People who get an influenza vaccine while pregnant or breastfeeding also develop antibodies against influenza that they can share with their infants through their breast milk. Getting vaccinated while pregnant also can help protect a baby from influenza after birth (because antibodies are passed to a developing baby during pregnancy). A common influenza sign, fever, has been associated in some studies with neural tube defects and other adverse outcomes for a developing baby. Influenza also may be harmful for the developing baby. Influenza is more likely to cause illness that results in hospitalization in pregnant people than in people of reproductive age who are not pregnant. Why should pregnant people get a flu shot?
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